Automated description from the Alliance of Genome Resources (Release 7.2.0)
Predicted to enable ubiquitin ligase activator activity; ubiquitin-protein transferase activity; and zinc ion binding activity. Predicted to be involved in cellular response to reactive oxygen species; protein import into peroxisome matrix, receptor recycling; and protein ubiquitination. Predicted to act upstream of or within protein transport. Predicted to be located in peroxisome. Predicted to be part of peroxisomal importomer complex. Predicted to be active in peroxisomal membrane. Is expressed in esophagus; lung; mandible; and maxilla. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 3A and peroxisome biogenesis disorder 3B. Orthologous to human PEX12 (peroxisomal biogenesis factor 12).
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