Automated description from the Alliance of Genome Resources (Release 7.5.0)
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity; positive regulation of biosynthetic process; and positive regulation of glomerular mesangial cell proliferation. Predicted to act upstream of or within regulation of proteolysis. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. Is expressed in olfactory epithelium. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; Nagashima-type palmoplantar keratosis; and familial encephalopathy with neuroserpin inclusion bodies. Orthologous to human SERPINB7 (serpin family B member 7).
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