Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in brain development; developmental growth; and negative regulation of transcription by RNA polymerase II. Acts upstream of or within adult feeding behavior and adult locomotory behavior. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; embryo ectoderm; limb bud; male reproductive gland or organ; and sensory organ. Orthologous to human DMBX1 (diencephalon/mesencephalon homeobox 1).
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