Automated description from the Alliance of Genome Resources (Release 7.2.0)
Predicted to enable protein transmembrane transporter activity. Acts upstream of or within SRP-dependent cotranslational protein targeting to membrane; liver development; and post-translational protein targeting to endoplasmic reticulum membrane. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of Sec62/Sec63 complex. Is expressed in several structures, including adrenal gland; brain; cardiovascular system; genitourinary system; and pancreas. Human ortholog(s) of this gene implicated in polycystic liver disease. Orthologous to human SEC63 (SEC63 homolog, protein translocation regulator).
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