Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables identical protein binding activity and molecular adaptor activity. Involved in several processes, including nervous system development; positive regulation of neuroblast proliferation; and regulation of synapse organization. Acts upstream of or within several processes, including detection of temperature stimulus involved in sensory perception of pain; mitochondrial calcium ion homeostasis; and non-motile cilium assembly. Located in microtubule organizing center; postsynaptic density; and synaptic vesicle. Is active in glutamatergic synapse. Is expressed in several structures, including brain; heart; liver; lung; and muscle tissue. Used to study melancholic depression and schizophrenia. Human ortholog(s) of this gene implicated in autism spectrum disorder (multiple); bipolar disorder; chronic fatigue syndrome; major depressive disorder; and psychotic disorder (multiple). Orthologous to human DISC1 (DISC1 scaffold protein).

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Gene Ontology Evidence Code Abbreviations:

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