Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables GDP-dissociation inhibitor activity and PH domain binding activity. Involved in several processes, including DNA damage response, signal transduction by p53 class mediator; negative regulation of TORC1 signaling; and negative regulation of translation in response to endoplasmic reticulum stress. Acts upstream of or within several processes, including positive regulation of lipophagy; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of protein kinase activity. Part of TORC2 complex and nucleotide-activated protein kinase complex. Is expressed in central nervous system; heart; and retina. Orthologous to human SESN2 (sestrin 2).

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Gene Ontology Evidence Code Abbreviations:

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