Automated description from the Alliance of Genome Resources (Release 7.5.0)
Enables miRNA binding activity and ubiquitin protein ligase activity. Involved in several processes, including G1/S transition of mitotic cell cycle; miRNA-mediated gene silencing by inhibition of translation; and protein autoubiquitination. Acts upstream of or within neural tube closure; positive regulation of miRNA-mediated gene silencing; and regulation of protein metabolic process. Located in P-body. Is expressed in several structures, including branchial arch; extraembryonic component; limb bud; nervous system; and reproductive system. Human ortholog(s) of this gene implicated in hydrocephalus. Orthologous to human TRIM71 (tripartite motif containing 71).
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