Gene Ontology Classifications

Symbol
Name
ID

Kir3dl2
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
MGI:3612791

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Predicted to enable several functions, including MHC class Ib protein binding activity; MHC class Ib receptor activity; and identical protein binding activity. Predicted to be involved in immune response-regulating signaling pathway. Predicted to be located in early endosome membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Polyomavirus-associated nephropathy; West Nile fever; human immunodeficiency virus infectious disease (multiple); liver disease (multiple); and tuberculosis (multiple). Orthologous to several human genes including KIR3DL1 (killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1) and KIR3DL2 (killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2).

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Aspect

Category

Evidence

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

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Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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