Automated description from the Alliance of Genome Resources (Release 7.5.0)
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; phosphopyruvate hydratase activity; and protein homodimerization activity. Predicted to be involved in several processes, including canonical glycolysis; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway; and regulation of primary metabolic process. Predicted to act upstream of or within glycolytic process. Predicted to be located in several cellular components, including growth cone; nuclear outer membrane; and synaptic membrane. Predicted to be part of phosphopyruvate hydratase complex. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human ENO1 (enolase 1).
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