Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable several functions, including heme binding activity; hemoglobin binding activity; and oxygen binding activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to be located in extracellular space. Predicted to be part of haptoglobin-hemoglobin complex and hemoglobin complex. Is expressed in blood; liver; and lung. Human ortholog(s) of this gene implicated in several diseases, including acute chest syndrome; congenital hemolytic anemia (multiple); polycythemia (multiple); sickle cell disease (multiple); and thalassemia (multiple). Orthologous to several human genes including HBB (hemoglobin subunit beta).
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