Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables adenylate cyclase binding activity and beta2-adrenergic receptor activity. Involved in cellular response to amyloid-beta; positive regulation of cold-induced thermogenesis; and positive regulation of signal transduction. Acts upstream of or within several processes, including bone resorption; brown fat cell differentiation; and diet induced thermogenesis. Located in apical plasma membrane and nucleus. Is active in neuronal dense core vesicle. Is expressed in several structures, including central nervous system; early conceptus; heart; liver; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); disease of metabolism (multiple); kidney failure (multiple); lung disease (multiple); and open-angle glaucoma (multiple). Orthologous to human ADRB2 (adrenoceptor beta 2).

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Gene Ontology Evidence Code Abbreviations:

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