Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables type 1 angiotensin receptor binding activity and type 2 angiotensin receptor binding activity. Involved in aldosterone secretion; positive regulation of cytokine production; and positive regulation of epithelial to mesenchymal transition. Acts upstream of or within several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of systemic arterial blood pressure by renin-angiotensin. Located in extracellular space. Is expressed in several structures, including axial skeleton; central nervous system; foregut mesenchyme; genitourinary system; and liver. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Orthologous to human AGT (angiotensinogen).

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Gene Ontology Evidence Code Abbreviations:

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