Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable high-density lipoprotein particle receptor binding activity; lipase inhibitor activity; and phospholipid binding activity. Acts upstream of or within cholesterol metabolic process; triglyceride catabolic process; and triglyceride mobilization. Predicted to be located in extracellular space. Predicted to be part of chylomicron; spherical high-density lipoprotein particle; and triglyceride-rich plasma lipoprotein particle. Human ortholog(s) of this gene implicated in several diseases, including apolipoprotein C-III deficiency; chronic kidney disease; familial hyperlipidemia (multiple); glucose metabolism disease (multiple); and hepatocellular carcinoma. Orthologous to human APOC3 (apolipoprotein C3).
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