Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable several functions, including BH3 domain binding activity; MDM2/MDM4 family protein binding activity; and enzyme binding activity. Acts upstream of or within several processes, including apoptotic signaling pathway; gonad development; and negative regulation of apoptotic process. Located in cytosol; endoplasmic reticulum; and mitochondrial outer membrane. Is expressed in several structures, including alimentary system; central nervous system; immune system; inner ear; and reproductive system. Human ortholog(s) of this gene implicated in breast cancer; carcinoma (multiple); leukemia (multiple); and pancreatic cancer. Orthologous to human BCL2L1 (BCL2 like 1).
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