Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Predicted to enable C5L2 anaphylatoxin chemotactic receptor binding activity and lipid binding activity. Involved in several processes, including nervous system development; positive regulation of endocytosis; and positive regulation of immune response. Acts upstream of or within several processes, including complement-dependent cytotoxicity; oviduct epithelium development; and positive regulation of immune response. Located in cell surface and extracellular space. Part of protein-containing complex. Is expressed in several structures, including adipose tissue; cerebral cortex; extraembryonic component; hemolymphoid system; and liver. Used to study complement component 3 deficiency. Human ortholog(s) of this gene implicated in several diseases, including complement deficiency (multiple); macular degeneration (multiple); paroxysmal nocturnal hemoglobinuria; sickle cell anemia; and silicosis. Orthologous to human C3 (complement C3).

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Gene Ontology Evidence Code Abbreviations:

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