Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Predicted to enable cytokine receptor activity; phospholipid binding activity; and protease binding activity. Predicted to contribute to serine-type endopeptidase activity. Predicted to be involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; activation of plasma proteins involved in acute inflammatory response; and positive regulation of signal transduction. Predicted to act upstream of or within positive regulation of interleukin-8 production. Predicted to be located in cell surface; collagen-containing extracellular matrix; and extracellular space. Predicted to be part of serine-type peptidase complex. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; egg cylinder; genitourinary system; gut; and respiratory system. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; COVID-19; disseminated intravascular coagulation; and von Willebrand's disease. Orthologous to human F3 (coagulation factor III, tissue factor).

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Gene Ontology Evidence Code Abbreviations:

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