Automated description from the Alliance of Genome Resources (Release 7.4.0)
Involved in positive regulation of dense core granule biogenesis. Acts upstream of or within protein localization to secretory granule. Predicted to be located in neuronal dense core vesicle and perinuclear region of cytoplasm. Predicted to be active in chromaffin granule and extracellular space. Is expressed in several structures, including adrenal gland; gut; male reproductive gland or organ; nervous system; and neural retina. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal disease; hypertension; and prostate cancer. Orthologous to human CHGA (chromogranin A).
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