Automated description from the Alliance of Genome Resources (Release 7.2.0)
Enables BMP binding activity; integrin binding activity; and protease binding activity. Involved in cartilage homeostasis and protein homooligomerization. Acts upstream of or within several processes, including BMP signaling pathway; cartilage development; and vasculature development. Located in extracellular space. Part of protein-containing complex. Is expressed in several structures, including connective tissue; embryo mesenchyme; notochord; placenta; and skeletal system. Used to study multiple epiphyseal dysplasia and pseudoachondroplasia. Human ortholog(s) of this gene implicated in carpal tunnel syndrome 2; multiple epiphyseal dysplasia 1; osteochondrodysplasia; and pseudoachondroplasia. Orthologous to human COMP (cartilage oligomeric matrix protein).
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