Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables peptidase activity. Acts upstream of or within brain renin-angiotensin system and zymogen activation. Located in extracellular space. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to several human genes including KLK1 (kallikrein 1).
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