Go Annotations as Summary Text (Tabular View) (GO Graph)

---

Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables S100 protein binding activity. Involved in several processes, including cellular response to amyloid-beta; negative regulation of long-term synaptic potentiation; and positive regulation of cytokine production. Acts upstream of or within several processes, including astrocyte development; induction of positive chemotaxis; and positive regulation of macromolecule metabolic process. Predicted to be located in several cellular components, including apical plasma membrane; basal plasma membrane; and fibrillar center. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and lung. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); cardiovascular system disease (multiple); cystic fibrosis; kidney failure (multiple); and lupus nephritis. Orthologous to human AGER (advanced glycosylation end-product specific receptor).

---

---

---

Gene Ontology Evidence Code Abbreviations:

---