Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in negative regulation of photoreceptor cell differentiation; positive regulation of amacrine cell differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including forebrain development; negative regulation of Notch signaling pathway; and negative regulation of oligodendrocyte differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; brain; branchial arch; genitourinary system; and sensory organ. Orthologous to human DLX1 (distal-less homeobox 1).
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