Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables nitric-oxide synthase binding activity. Involved in several processes, including negative regulation of protein modification process; positive regulation of cell-matrix adhesion; and regulation of monoatomic cation transmembrane transport. Acts upstream of with a positive effect on cholinergic synaptic transmission. Acts upstream of or within several processes, including determination of adult lifespan; muscle cell cellular homeostasis; and nervous system development. Located in several cellular components, including Z disc; cell-substrate junction; and sarcolemma. Part of dystrophin-associated glycoprotein complex. Is active in GABA-ergic synapse and postsynaptic specialization. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genital tubercle; and musculature. Used to study Becker muscular dystrophy and Duchenne muscular dystrophy. Human ortholog(s) of this gene implicated in cognitive disorder; dilated cardiomyopathy (multiple); intellectual disability; and muscular dystrophy (multiple). Orthologous to human DMD (dystrophin).

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Gene Ontology Evidence Code Abbreviations:

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