Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables non-membrane spanning protein tyrosine kinase activity. Involved in several processes, including positive regulation of ubiquitin-dependent protein catabolic process; protein phosphorylation; and regulation of modification of postsynaptic actin cytoskeleton. Acts upstream of or within several processes, including blood vessel morphogenesis; generation of neurons; and negative regulation of nervous system development. Located in several cellular components, including apical plasma membrane; focal adhesion; and lamellipodium. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and vault of skull. Human ortholog(s) of this gene implicated in leiomyoma; lung small cell carcinoma; and pulmonary hypertension. Orthologous to human PTK2 (protein tyrosine kinase 2).

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Gene Ontology Evidence Code Abbreviations:

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