Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable fibroblast growth factor binding activity; fibroblast growth factor receptor activity; and heparin binding activity. Involved in several processes, including cholesterol homeostasis; phosphate ion homeostasis; and regulation of bile acid biosynthetic process. Acts upstream of or within several processes, including alveolar secondary septum development; negative regulation of fibroblast growth factor production; and positive regulation of parathyroid hormone secretion. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and transport vesicle. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Predicted to colocalize with cell-cell junction. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in carcinoma (multiple); liver cirrhosis; prostate cancer; and stomach cancer. Orthologous to human FGFR4 (fibroblast growth factor receptor 4).
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