Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables several functions, including cytoskeletal protein binding activity; protein tyrosine kinase activity; and transmembrane transporter binding activity. Involved in several processes, including negative regulation of dendritic spine maintenance; positive regulation of tyrosine phosphorylation of STAT protein; and reelin-mediated signaling pathway. Acts upstream of or within several processes, including activated T cell proliferation; negative regulation of protein metabolic process; and nervous system development. Located in several cellular components, including actin filament; membrane raft; and postsynaptic density. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study skin disease and skin squamous cell carcinoma. Human ortholog(s) of this gene implicated in Alzheimer's disease and schizophrenia. Orthologous to human FYN (FYN proto-oncogene, Src family tyrosine kinase).
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