Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.5.0)

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; p53 binding activity; and transcription coactivator binding activity. Involved in platelet aggregation; regulation of definitive erythrocyte differentiation; and regulation of primary metabolic process. Acts upstream of or within several processes, including hemopoiesis; positive regulation of osteoblast proliferation; and regulation of primitive erythrocyte differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and mesenchyme derived from lateral plate. Used to study myelodysplastic syndrome; myelofibrosis; and thrombocytopenia. Human ortholog(s) of this gene implicated in several diseases, including X-linked recessive disease (multiple); beta thalassemia; colon adenocarcinoma; depressive disorder; and hematologic cancer (multiple). Orthologous to human GATA1 (GATA binding protein 1).

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Gene Ontology Evidence Code Abbreviations:

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