Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity and lactose synthase activity. Involved in lactose biosynthetic process. Acts upstream of or within several processes, including binding activity of sperm to zona pellucida; penetration of zona pellucida; and regulation of epithelial cell proliferation. Located in Golgi apparatus; cell surface; and plasma membrane. Part of protein-containing complex. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; liver; and nervous system. Used to study IgA glomerulonephritis and endocrine system disease. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation and congenital disorder of glycosylation type IId. Orthologous to human B4GALT1 (beta-1,4-galactosyltransferase 1).
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