Automated description from the Alliance of Genome Resources (Release 7.2.0)
Predicted to enable kainate selective glutamate receptor activity; ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential; and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to act upstream of or within monoatomic ion transmembrane transport. Located in postsynaptic membrane and presynaptic membrane. Part of kainate selective glutamate receptor complex. Is active in hippocampal mossy fiber to CA3 synapse. Is expressed in brain; retina; and spinal cord. Orthologous to human GRIK4 (glutamate ionotropic receptor kainate type subunit 4).
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