Go Annotations as Summary Text (Tabular View)

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Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable several functions, including beta-2-microglobulin binding activity; peptide antigen binding activity; and signaling receptor binding activity. Acts upstream of or within inner ear development. Predicted to be located in several cellular components, including Golgi apparatus; cell surface; and endoplasmic reticulum. Predicted to be part of MHC class I protein complex and MHC class Ib protein complex. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; lung; and musculoskeletal system. Human ortholog(s) of this gene implicated in several diseases, including Stevens-Johnson syndrome; asthma (multiple); autoimmune disease (multiple); eye disease (multiple); and inner ear disease (multiple). Orthologous to human HLA-B (major histocompatibility complex, class I, B); HLA-C (major histocompatibility complex, class I, C); and HLA-E (major histocompatibility complex, class I, E).

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Gene Ontology Evidence Code Abbreviations:

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