Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables signaling receptor activator activity and signaling receptor binding activity. Involved in several processes, including negative regulation of release of cytochrome c from mitochondria; positive regulation of myelination; and postsynaptic modulation of chemical synaptic transmission. Acts upstream of or within several processes, including lung development; positive regulation of cell population proliferation; and prostate gland development. Located in exocytic vesicle and extracellular space. Is active in glutamatergic synapse and neuronal dense core vesicle lumen. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including acne; artery disease (multiple); diabetes mellitus (multiple); myopia; and neurodegenerative disease (multiple). Orthologous to human IGF1 (insulin like growth factor 1).

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Gene Ontology Evidence Code Abbreviations:

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