Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables cytokine activity and interleukin-6 receptor binding activity. Involved in several processes, including liver development; lymphocyte activation involved in immune response; and positive regulation of macromolecule biosynthetic process. Acts upstream of or within with a positive effect on gene expression. Acts upstream of or within several processes, including positive regulation of cell population proliferation; regulation of gene expression; and salivary gland morphogenesis. Located in external side of plasma membrane. Part of interleukin-6 receptor complex. Is active in extracellular space. Is expressed in several structures, including adrenal gland; early conceptus; genitourinary system; hemolymphoid system; and intestine. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and periodontal disease (multiple). Orthologous to human IL6 (interleukin 6).
This site uses cookies.
Some cookies are essential for site operations and others help us analyze use and utility of our web site.
Please refer to our
privacy policy
for more information.