Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables mannose-6-phosphate isomerase activity. Involved in GDP-mannose biosynthetic process from glucose. Acts upstream of or within mannose to fructose-6-phosphate catabolic process. Is active in cytosol. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder and congenital disorder of glycosylation Ib. Orthologous to human MPI (mannose phosphate isomerase).
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