Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables guanosine phosphorylase activity and purine-nucleoside phosphorylase activity. Involved in several processes, including allantoin metabolic process; purine nucleoside catabolic process; and purine nucleoside monophosphate metabolic process. Acts upstream of or within several processes, including guanosine catabolic process; positive regulation of lymphocyte activation; and purine nucleoside triphosphate metabolic process. Is active in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Used to study purine nucleoside phosphorylase deficiency. Human ortholog(s) of this gene implicated in purine nucleoside phosphorylase deficiency and purine-pyrimidine metabolic disorder. Orthologous to human PNP (purine nucleoside phosphorylase).

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Gene Ontology Evidence Code Abbreviations:

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