Automated description from the Alliance of Genome Resources (Release 7.2.0)
Predicted to enable pyruvate dehydrogenase (acetyl-transferring) activity. Predicted to contribute to pyruvate dehydrogenase (NAD+) activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Predicted to act upstream of or within glucose metabolic process and tricarboxylic acid cycle. Located in mitochondrion. Is expressed in nervous system; testis; and ventricle cardiac muscle. Human ortholog(s) of this gene implicated in spermatogenic failure. Orthologous to human PDHA2 (pyruvate dehydrogenase E1 subunit alpha 2).
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