Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables several functions, including ATP hydrolysis activity; ATPase-coupled intramembrane lipid transporter activity; and xenobiotic transmembrane transporter activity. Involved in several processes, including lipid translocation; terpenoid transport; and xenobiotic transport across blood-brain barrier. Acts upstream of or within xenobiotic detoxification by transmembrane export across the plasma membrane. Located in apical plasma membrane and intercellular canaliculus. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and integumental system. Used to study inflammatory bowel disease 13. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); drug dependence (multiple); human immunodeficiency virus infectious disease (multiple); inflammatory bowel disease (multiple); and leukemia (multiple). Orthologous to human ABCB1 (ATP binding cassette subfamily B member 1).

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Gene Ontology Evidence Code Abbreviations:

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