Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables phosphatidylinositol phospholipase C activity and phosphorylation-dependent protein binding activity. Involved in several processes, including immune response-activating signaling pathway; positive regulation of cytokine production; and positive regulation of protein phosphorylation. Acts upstream of or within several processes, including activation of store-operated calcium channel activity; follicular B cell differentiation; and regulation of calcium-mediated signaling. Located in cytosol and membrane raft. Is expressed in several structures, including alimentary system; bone; cardiovascular system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in familial cold autoinflammatory syndrome 3. Orthologous to human PLCG2 (phospholipase C gamma 2).

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Gene Ontology Evidence Code Abbreviations:

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