Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.5.0)

Enables G protein-coupled receptor binding activity; identical protein binding activity; and lipid antigen binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; cellular response to reactive oxygen species; and positive regulation of MAPK cascade. Acts upstream of or within with a negative effect on gene expression. Acts upstream of or within several processes, including glycosylceramide metabolic process; prostate gland development; and protein transport. Located in aggresome; extracellular region; and lysosome. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and sensory organ. Used to study Gaucher's disease; Krabbe disease; combined saposin deficiency; and metachromatic leukodystrophy. Human ortholog(s) of this gene implicated in atypical Gaucher's disease due to saposin c deficiency; combined saposin deficiency; and late onset Parkinson's disease. Orthologous to human PSAP (prosaposin).

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Gene Ontology Evidence Code Abbreviations:

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