Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables heme binding activity; prostaglandin-endoperoxide synthase activity; and protein homodimerization activity. Involved in several processes, including brown fat cell differentiation; negative regulation of apoptotic process; and regulation of inflammatory response. Acts upstream of or within several processes, including decidualization; prostaglandin secretion; and response to nematode. Located in cytoplasm; neuron projection; and nuclear membrane. Is expressed in several structures, including early embryo; gut; limb long bone; skin; and urinary system. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; artery disease (multiple); arthritis (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human PTGS2 (prostaglandin-endoperoxide synthase 2).

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Gene Ontology Evidence Code Abbreviations:

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