Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables DNA binding activity; DNA-binding transcription factor activity; and transcription coactivator binding activity. Contributes to nuclear receptor activity and transcription cis-regulatory region binding activity. Involved in several processes, including mRNA transcription by RNA polymerase II; positive regulation of thyroid hormone receptor signaling pathway; and retinoic acid receptor signaling pathway. Acts upstream of or within several processes, including cardiac muscle tissue development; regulation of branching involved in prostate gland morphogenesis; and regulation of gene expression. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver; and sensory organ. Used to study congenital heart disease; dilated cardiomyopathy; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RXRA (retinoid X receptor alpha).

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Gene Ontology Evidence Code Abbreviations:

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