Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; neuronal stem cell population maintenance; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including forebrain development; respiratory system development; and sensory organ morphogenesis. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is active in chromatin. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer; nasal cavity cancer; and syndromic microphthalmia 3. Orthologous to human SOX2 (SRY-box transcription factor 2).

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Gene Ontology Evidence Code Abbreviations:

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