Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables several functions, including DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and histone deacetylase binding activity. Involved in several processes, including circulatory system development; embryonic morphogenesis; and regulation of transcription by RNA polymerase II. Acts upstream of with a negative effect on pigment metabolic process involved in pigmentation. Acts upstream of or within several processes, including heart development; mammary placode formation; and ureteric peristalsis. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in atrial heart septal defect; heart septal defect; and vertebral anomalies and variable endocrine and T-cell dysfunction. Orthologous to human TBX2 (T-box transcription factor 2).

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Gene Ontology Evidence Code Abbreviations:

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