Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; identical protein binding activity; and protein dimerization activity. Involved in several processes, including D-glucose transmembrane transport; glucose homeostasis; and positive regulation of DNA-templated transcription. Acts upstream of or within several processes, including embryonic morphogenesis; monocarboxylic acid biosynthetic process; and monocarboxylic acid transport. Located in cytoplasm; photoreceptor outer segment; and pronucleus. Part of transcription regulator complex. Is expressed in several structures, including extraembryonic component; genitourinary system; gut; septum transversum hepatic component; and spleen. Used to study maturity-onset diabetes of the young type 3; phenylketonuria; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebral infarction; glucose metabolism disease (multiple); liver disease (multiple); and renal cell carcinoma. Orthologous to human HNF1A (HNF1 homeobox A).

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Gene Ontology Evidence Code Abbreviations:

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