Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables connexin binding activity and protein domain specific binding activity. Involved in several processes, including ameloblast differentiation; negative regulation of stress fiber assembly; and positive regulation of sprouting angiogenesis. Acts upstream of or within blastocyst formation and sensory perception of sound. Located in several cellular components, including apicolateral plasma membrane; bicellular tight junction; and intercellular canaliculus. Part of protein-containing complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Orthologous to human TJP1 (tight junction protein 1).
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