Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Predicted to enable several functions, including identical protein binding activity; integrin binding activity; and protein-folding chaperone binding activity. Acts upstream of or within several processes, including activation of blood coagulation via clotting cascade; liver development; and platelet activation. Located in Weibel-Palade body; external side of plasma membrane; and extracellular space. Is expressed in several structures, including cardiovascular system; extraembryonic component; genitourinary system; immune system; and pancreas vasculature. Used to study von Willebrand's disease and von Willebrand's disease 2. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; Bernard-Soulier syndrome; end stage renal disease; essential thrombocythemia; and von Willebrand's disease (multiple). Orthologous to human VWF (von Willebrand factor).

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Gene Ontology Evidence Code Abbreviations:

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