Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein kinase binding activity. Involved in several processes, including mitochondrion organization; positive regulation of macromolecule biosynthetic process; and ventricular cardiac myofibril assembly. Acts upstream of or within positive regulation of D-glucose import and positive regulation of DNA-templated transcription. Located in chromatin and nucleus. Is expressed in several structures, including brain; embryo mesenchyme; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human MEF2A (myocyte enhancer factor 2A).
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