Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables DNA-directed DNA polymerase activity. Involved in DNA replication initiation and DNA replication, synthesis of primer. Acts upstream of or within DNA replication. Located in nucleus. Part of alpha DNA polymerase:primase complex. Human ortholog(s) of this gene implicated in Van Esch-O'Driscoll syndrome and X-linked reticulate pigmentary disorder. Orthologous to human POLA1 (DNA polymerase alpha 1, catalytic subunit).
This site uses cookies.
Some cookies are essential for site operations and others help us analyze use and utility of our web site.
Please refer to our
privacy policy
for more information.