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Gene Expression Literature Detail
Symbol
Name
ID
Spo11
SPO11 initiator of meiotic double stranded breaks
MGI:1349669

Reference
J:164916 Bellani MA, Boateng KA, McLeod D, Camerini-Otero RD, The expression profile of the major mouse SPO11 isoforms indicates that SPO11beta introduces double strand breaks and suggests that SPO11alpha has an additional role in prophase in both spermatocytes and oocytes. Mol Cell Biol. 2010 Sep;30(18):4391-403



red ball Indicates gene expression was analyzed but not necessarily detected.
Age E14.5 E20 E P
Immunohistochemistry (section)
In situ RNA (section)
Immunohistochemistry (whole mount) red ball
In situ RNA (whole mount)
In situ reporter (knock in)
Northern blot
Western blot red ball
RT-PCR red ball red ball red ball red ball
cDNA clones
RNase protection
Nuclease S1
Primer Extension

Comments: Age of embryo at noon of plug day not specified in reference. Authors state that expression was examined on dpc 14.5-20; not all stages are detailed. The protein was immunoprecipitated prior to Western blotting.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory