About   Help   FAQ
Gene Expression Literature Detail
Symbol
Name
ID
Parp1
poly (ADP-ribose) polymerase family, member 1
MGI:1340806

Reference
J:69602 Hohenstein P, Kielman MF, Breukel C, Bennett LM, Wiseman R, Krimpenfort P, Cornelisse C, van Ommen GJ, Devilee P, Fodde R, A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage. Oncogene. 2001 May 3;20(20):2544-50



red ball Indicates gene expression was analyzed but not necessarily detected.
Age E9.5 E10.5
Immunohistochemistry (section) red ball red ball
In situ RNA (section)
Immunohistochemistry (whole mount)
In situ RNA (whole mount)
In situ reporter (knock in)
Northern blot
Western blot
RT-PCR
cDNA clones
RNase protection
Nuclease S1
Primer Extension

Comments: During apoptosis this protein is a substrate for caspase-3 cleavage. The antibody they used only recognizes the p85 cleavage fragment of this protein. Age of embryo at noon of plug day not specified in reference.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory