Gene Expression Literature Summary

• Symbol: Serpine2
• Name: serine (or cysteine) peptidase inhibitor, clade E, member 2
• ID: MGI:101780

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E9.5	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15.5	E16.5	E17	E18.5	E	P
Immunohistochemistry (section)											1						2
In situ RNA (section)	1	2	2		3		2		2		3		1	1	1	1	4
In situ RNA (whole mount)		1	1		1		2		2			1	1
In situ reporter (knock in)													1		1		1
Northern blot	1																1
Western blot																	1
RT-PCR				1	1	1	2	2	1	2	1		2		1	1
cDNA clones					1		2		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Serpine2  serine (or cysteine) peptidase inhibitor, clade E, member 2   (Synonyms: B230326M24Rik, nexin, PI7, PN-1, protease nexin 1, Spi4)
Results	Reference
2	J:98922 Bouma GJ, Albrecht KH, Washburn LL, Recknagel AK, Churchill GA, Eicher EM, Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells. Development. 2005 Jul;132(13):3045-54
7*	J:93500 Bouma GJ, Hart GT, Washburn LL, Recknagel AK, Eicher EM, Using real time RT-PCR analysis to determine multiple gene expression patterns during XX and XY mouse fetal gonad development. Gene Expr Patterns. 2004 Nov;5(1):141-9
2	J:103829 Chen B, Schaevitz LR, McConnell SK, Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex. Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17184-9
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:333882 Ehrman JM, Merchan-Sala P, Ehrman LA, Chen B, Lim HW, Waclaw RR, Campbell K, Formation of the Mouse Internal Capsule and Cerebral Peduncle: A Pioneering Role for Striatonigral Axons as Revealed in Isl1 Conditional Mutants. J Neurosci. 2022 Apr 20;42(16):3344-3364
4	J:139818 Feutz AC, Barrandon Y, Monard D, Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells. J Cell Sci. 2008 May 1;121(Pt 9):1435-43
1	J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24
8*	J:62920 Grimmond S, Hateren NV, Siggers P, Arkell R, Larder R, Soares MB, Bonaldo Md, Smith L, Tymowska-Lalanne Z, Wells C, Greenfield A, Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development. Hum Mol Genet. 2000 Jun 12;9(10):1553-60
4	J:328996 Kastriti ME, Faure L, Von Ahsen D, Bouderlique TG, Bostrom J, Solovieva T, Jackson C, Bronner M, Meijer D, Hadjab S, Lallemend F, Erickson A, Kaucka M, Dyachuk V, Perlmann T, Lahti L, Krivanek J, Brunet JF, Fried K, Adameyko I, Schwann cell precursors represent a neural crest-like state with biased multipotency. EMBO J. 2022 Sep 1;41(17):e108780
3*	J:39349 Kury P, Schaeren-Wiemers N, Monard D, Protease nexin-1 is expressed at the mouse met-/mesencephalic junction and FGF signaling regulates its promoter activity in primary met-/mesencephalic cells. Development. 1997 Mar;124(6):1251-62
15*	J:16551 Mansuy IM, van der Putten H, Schmid P, Meins M, Botteri FM, Monard D, Variable and multiple expression of Protease Nexin-1 during mouse organogenesis and nervous system development. Development. 1993 Dec;119(4):1119-34
1*	J:86589 McClive PJ, Hurley TM, Sarraj MA, van den Bergen JA, Sinclair AH, Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad. Genesis. 2003 Oct;37(2):84-90
2*	J:81347 Menke DB, Page DC, Sexually dimorphic gene expression in the developing mouse gonad. Gene Expr Patterns. 2002 Dec;2(3-4):359-67
1*	J:205051 Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, Sestan N, Gage FH, Lein ES, Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
1	J:154029 Munger SC, Aylor DL, Syed HA, Magwene PM, Threadgill DW, Capel B, Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal. Genes Dev. 2009 Nov 1;23(21):2521-36
1	J:124280 Nieuwenhuis E, Barnfield PC, Makino S, Hui CC, Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1. Dev Biol. 2007 Aug 15;308(2):547-60
2	J:88700 Odet F, Guyot R, Leduque P, Le Magueresse-Battistoni B, Evidence for similar expression of protein C inhibitor and the urokinase-type plasminogen activator system during mouse testis development. Endocrinology. 2004 Mar;145(3):1481-9
1*	J:198109 Oeschger FM, Wang WZ, Lee S, Garcia-Moreno F, Goffinet AM, Arbones ML, Rakic S, Molnar Z, Gene expression analysis of the embryonic subplate. Cereb Cortex. 2012 Jun;22(6):1343-59
2*	J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188
1*	J:239225 Scott KK, Norris RA, Potter SS, Norrington DW, Baybo MA, Hicklin DM, Kern MJ, GeneChip microarrays facilitate identification of Protease Nexin-1 as a target gene of the Prx2 (S8) homeoprotein. DNA Cell Biol. 2003 Feb;22(2):95-105