Gene Expression Literature Summary
|
Symbol Name ID |
Pou5f1
POU domain, class 5, transcription factor 1 MGI:101893 |
| Age | E0.5 | E1 | E1.5 | E2 | E2.5 | E3 | E3.5 | E4 | E4.5 | E5 | E5.5 | E6 | E6.5 | E7 | E7.5 | E8 | E8.5 | E9 | E9.5 | E10 | E10.5 | E11 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E19 | E19.5 | E | P |
| Immunohistochemistry (section) | 1 | 1 | 4 | 1 | 18 | 6 | 24 | 4 | 32 | 6 | 33 | 13 | 31 | 4 | 17 | 3 | 16 | 1 | 14 | 1 | 28 | 5 | 21 | 2 | 32 | 18 | 6 | 8 | 2 | 3 | 2 | 1 | 1 | 3 | 20 | ||||||
| In situ RNA (section) | 1 | 1 | 1 | 2 | 1 | 4 | 2 | 2 | 2 | 3 | 7 | 1 | 9 | 4 | 5 | 3 | 2 | 2 | 6 | 1 | 2 | 17 | 2 | 3 | 1 | 4 | 1 | 2 | 10 | ||||||||||||
| Immunohistochemistry (whole mount) | 7 | 9 | 2 | 5 | 17 | 21 | 73 | 16 | 28 | 4 | 13 | 3 | 14 | 4 | 9 | 1 | 5 | 3 | 3 | 3 | 1 | 1 | 1 | 2 | 4 | ||||||||||||||||
| In situ RNA (whole mount) | 2 | 3 | 3 | 3 | 3 | 8 | 4 | 7 | 7 | 13 | 5 | 33 | 9 | 35 | 11 | 15 | 3 | 8 | 7 | 1 | 9 | 13 | 2 | 20 | 10 | 6 | 2 | 3 | 1 | ||||||||||||
| In situ reporter (knock in) | 1 | ||||||||||||||||||||||||||||||||||||||||
| Northern blot | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 4 | ||||||||||||||||||||||||||||||||
| Western blot | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 3 | 1 | 2 | 1 | 1 | 6 | ||||||||||||||||||||||||||||
| RT-PCR | 12 | 18 | 5 | 17 | 20 | 18 | 47 | 7 | 9 | 1 | 2 | 19 | 4 | 17 | 2 | 13 | 3 | 8 | 2 | 7 | 9 | 2 | 16 | 25 | 2 | 19 | 1 | 18 | 7 | 8 | 12 | 2 | 4 | 49 | |||||||
| cDNA clones | 1 | 1 | |||||||||||||||||||||||||||||||||||||||
| RNase protection | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 |
| Pou5f1 POU domain, class 5, transcription factor 1 (Synonyms: Oct-3, Oct-3/4, Oct3/4, Oct-4, Oct4, Otf-3, Otf3, Otf3g, Otf3-rs7, Otf-4, Otf4) | |
| Results | Reference |
| 1 | J:222738 Abboud N, Moore-Morris T, Hiriart E, Yang H, Bezerra H, Gualazzi MG, Stefanovic S, Guenantin AC, Evans SM, Puceat M, A cohesin-OCT4 complex mediates Sox enhancers to prime an early embryonic lineage. Nat Commun. 2015;6:6749 |
| 1* | J:231231 Abby E, Tourpin S, Ribeiro J, Daniel K, Messiaen S, Moison D, Guerquin J, Gaillard JC, Armengaud J, Langa F, Toth A, Martini E, Livera G, Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts. Nat Commun. 2016;7:10324 |
| 2 | J:332401 Abuhashem A, Chivu AG, Zhao Y, Rice EJ, Siepel A, Danko CG, Hadjantonakis AK, RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription. Genes Dev. 2022 Aug 18;36(13-14):770-89 |
| 2 | J:191079 Acampora D, Di Giovannantonio LG, Simeone A, Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition. Development. 2013 Jan 1;140(1):43-55 |
| 7 | J:238298 Acampora D, Omodei D, Petrosino G, Garofalo A, Savarese M, Nigro V, Di Giovannantonio LG, Mercadante V, Simeone A, Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast. Cell Rep. 2016 Jun 21;15(12):2651-64 |
| 6* | J:118938 Adachi K, Soeta-Saneyoshi C, Sagara H, Iwakura Y, Crucial role of Bysl in mammalian preimplantation development as an integral factor for 40S ribosome biogenesis. Mol Cell Biol. 2007 Mar;27(6):2202-14 |
| 2 | J:306539 Aeby E, Lee HG, Lee YW, Kriz A, Del Rosario BC, Oh HJ, Boukhali M, Haas W, Lee JT, Decapping enzyme 1A breaks X-chromosome symmetry by controlling Tsix elongation and RNA turnover. Nat Cell Biol. 2020 Sep;22(9):1116-1129 |
| 1 | J:160922 Ahmed K, Dehghani H, Rugg-Gunn P, Fussner E, Rossant J, Bazett-Jones DP, Global chromatin architecture reflects pluripotency and lineage commitment in the early mouse embryo. PLoS One. 2010;5(5):e10531 |
| 2* | J:236309 Aires R, Jurberg AD, Leal F, Novoa A, Cohn MJ, Mallo M, Oct4 Is a Key Regulator of Vertebrate Trunk Length Diversity. Dev Cell. 2016 Aug 8;38(3):262-74 |
| 1 | J:146589 Akamatsu W, DeVeale B, Okano H, Cooney AJ, van der Kooy D, Suppression of Oct4 by germ cell nuclear factor restricts pluripotency and promotes neural stem cell development in the early neural lineage. J Neurosci. 2009 Feb 18;29(7):2113-24 |
| 2 | J:195303 Aksoy I, Jauch R, Chen J, Dyla M, Divakar U, Bogu GK, Teo R, Leng Ng CK, Herath W, Lili S, Hutchins AP, Robson P, Kolatkar PR, Stanton LW, Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm. EMBO J. 2013 Apr 3;32(7):938-53 |
| 2 | J:163855 Alder O, Lavial F, Helness A, Brookes E, Pinho S, Chandrashekran A, Arnaud P, Pombo A, O'Neill L, Azuara V, Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment. Development. 2010 Aug 1;137(15):2483-92 |
| 3 | J:326354 Allegre N, Chauveau S, Dennis C, Renaud Y, Meistermann D, Estrella LV, Pouchin P, Cohen-Tannoudji M, David L, Chazaud C, NANOG initiates epiblast fate through the coordination of pluripotency genes expression. Nat Commun. 2022 Jun 21;13(1):3550 |
| 1* | J:239949 Amakawa Y, Sakata Y, Hoki Y, Arata S, Shioda S, Fukagawa T, Sasaki H, Sado T, A new Xist allele driven by a constitutively active promoter is dominated by Xist locus environment and exhibits the parent-of-origin effects. Development. 2015 Dec 15;142(24):4299-308 |
| 1 | J:270141 An Y, Sekinaka T, Tando Y, Okamura D, Tanaka K, Ito-Matsuoka Y, Takehara A, Yaegashi N, Matsui Y, Derivation of pluripotent stem cells from nascent undifferentiated teratoma. Dev Biol. 2019 Feb 1;446(1):43-55 |
| 1* | J:55247 Anderson R, Fassler R, Georges-Labouesse E, Hynes RO, Bader BL, Kreidberg JA, Schaible K, Heasman J, Wylie C, Mouse primordial germ cells lacking beta1 integrins enter the germline but fail to migrate normally to the gonads. Development. 1999 Apr;126(8):1655-64 |
| 1* | J:184591 Aoyama M, Sun-Wada GH, Yamamoto A, Yamamoto M, Hamada H, Wada Y, Spatial Restriction of Bone Morphogenetic Protein Signaling in Mouse Gastrula through the mVam2-Dependent Endocytic Pathway. Dev Cell. 2012 Jun 12;22(6):1163-75 |
| 1 | J:247201 Arora R, Abby E, Ross AD, Cantu AV, Kissner MD, Castro V, Ho HY, Livera G, Laird DJ, Meiotic onset is reliant on spatial distribution but independent of germ cell number in the mouse ovary. J Cell Sci. 2016 Jul 01;129(13):2493-9 |
| 2* | J:81180 Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, Lovell-Badge R, Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev. 2003 Jan 1;17(1):126-40 |
| 2 | J:245724 Azami T, Waku T, Matsumoto K, Jeon H, Muratani M, Kawashima A, Yanagisawa J, Manabe I, Nagai R, Kunath T, Nakamura T, Kurimoto K, Saitou M, Takahashi S, Ema M, Klf5 maintains the balance of primitive endoderm versus epiblast specification during mouse embryonic development by suppression of Fgf4. Development. 2017 Oct 15;144(20):3706-3718 |
| 3 | J:314663 Bang J, Han M, Yoo TJ, Qiao L, Jung J, Na J, Carlson BA, Gladyshev VN, Hatfield DL, Kim JH, Kim LK, Lee BJ, Identification of Signaling Pathways for Early Embryonic Lethality and Developmental Retardation in Sephs1(-/-) Mice. Int J Mol Sci. 2021 Oct 28;22(21) |
| 1 | J:130205 Barrow JR, Howell WD, Rule M, Hayashi S, Thomas KR, Capecchi MR, McMahon AP, Wnt3 signaling in the epiblast is required for proper orientation of the anteroposterior axis. Dev Biol. 2007 Dec 1;312(1):312-20 |
| 1* | J:99569 Barrow KM, Ward CM, Rutter J, Ali S, Stern PL, Embryonic expression of murine 5T4 oncofoetal antigen is associated with morphogenetic events at implantation and in developing epithelia. Dev Dyn. 2005 Aug;233(4):1535-45 |
| 1 | J:253960 Basilicata MF, Frank M, Solter D, Brabletz T, Stemmler MP, Inappropriate cadherin switching in the mouse epiblast compromises proper signaling between the epiblast and the extraembryonic ectoderm during gastrulation. Sci Rep. 2016 May 24;6:26562 |
| 1 | J:81247 Beck S, Le Good JA, Guzman M, Ben Haim N, Roy K, Beermann F, Constam DB, Extraembryonic proteases regulate Nodal signalling during gastrulation. Nat Cell Biol. 2002 Dec;4(12):981-5 |
| 1* | J:329966 Bell CJ, Gupta N, Tremblay KD, Mager J, Borcs6 is required for endo-lysosomal degradation during early development. Mol Reprod Dev. 2022 Aug;89(8):337-350 |
| 1 | J:201097 Beraldo FH, Soares IN, Goncalves DF, Fan J, Thomas AA, Santos TG, Mohammad AH, Roffe M, Calder MD, Nikolova S, Hajj GN, Guimaraes AL, Massensini AR, Welch I, Betts DH, Gros R, Drangova M, Watson AJ, Bartha R, Prado VF, Martins VR, Prado MA, Stress-inducible phosphoprotein 1 has unique cochaperone activity during development and regulates cellular response to ischemia via the prion protein. FASEB J. 2013 Sep;27(9):3594-607 |
| 5* | J:264256 Bernardo AS, Jouneau A, Marks H, Kensche P, Kobolak J, Freude K, Hall V, Feher A, Polgar Z, Sartori C, Bock I, Louet C, Faial T, Kerstens HHD, Bouissou C, Parsonage G, Mashayekhi K, Smith JC, Lazzari G, Hyttel P, Stunnenberg HG, Huynen M, Pedersen RA, Dinnyes A, Mammalian embryo comparison identifies novel pluripotency genes associated with the naive or primed state. Biol Open. 2018 Aug 17;7(8):bio033282 |
| 1* | J:86391 Bernstein E, Kim SY, Carmell MA, Murchison EP, Alcorn H, Li MZ, Mills AA, Elledge SJ, Anderson KV, Hannon GJ, Dicer is essential for mouse development. Nat Genet. 2003 Nov;35(3):215-7 |
| 1 | J:221596 Bertero A, Madrigal P, Galli A, Hubner NC, Moreno I, Burks D, Brown S, Pedersen RA, Gaffney D, Mendjan S, Pauklin S, Vallier L, Activin/nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions by controlling the H3K4me3 chromatin mark. Genes Dev. 2015 Apr 1;29(7):702-17 |
| 2 | J:227651 Bessonnard S, Mesnard D, Constam DB, PC7 and the related proteases Furin and Pace4 regulate E-cadherin function during blastocyst formation. J Cell Biol. 2015 Sep 28;210(7):1185-97 |
| 1 | J:201276 Betschinger J, Nichols J, Dietmann S, Corrin PD, Paddison PJ, Smith A, Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3. Cell. 2013 Apr 11;153(2):335-47 |
| 1* | J:150223 Beverdam A, Svingen T, Bagheri-Fam S, Bernard P, McClive P, Robson M, Khojasteh MB, Salehi M, Sinclair AH, Harley VR, Koopman P, Sox9-dependent expression of Gstm6 in Sertoli cells during testis development in mice. Reproduction. 2009 Mar;137(3):481-6 |
| 2 | J:254597 Bhargava S, Cox B, Polydorou C, Gresakova V, Korinek V, Strnad H, Sedlacek R, Epp TA, Chawengsaksophak K, The epigenetic modifier Fam208a is required to maintain epiblast cell fitness. Sci Rep. 2017 Aug 24;7(1):9322 |
| 1* | J:198636 Biechele S, Cockburn K, Lanner F, Cox BJ, Rossant J, Porcn-dependent Wnt signaling is not required prior to mouse gastrulation. Development. 2013 Jul;140(14):2961-71 |
| 2 | J:74982 Bleckmann SC, Blendy JA, Rudolph D, Monaghan AP, Schmid W, Schutz G, Activating transcription factor 1 and CREB are important for cell survival during early mouse development. Mol Cell Biol. 2002 Mar;22(6):1919-25 |
| 2 | J:153050 Bogani D, Siggers P, Brixey R, Warr N, Beddow S, Edwards J, Williams D, Wilhelm D, Koopman P, Flavell RA, Chi H, Ostrer H, Wells S, Cheeseman M, Greenfield A, Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. PLoS Biol. 2009 Sep;7(9):e1000196 |
| 3 | J:340618 Bondarenko V, Nikolaev M, Kromm D, Belousov R, Wolny A, Blotenburg M, Zeller P, Rezakhani S, Hugger J, Uhlmann V, Hufnagel L, Kreshuk A, Ellenberg J, van Oudenaarden A, Erzberger A, Lutolf MP, Hiiragi T, Embryo-uterine interaction coordinates mouse embryogenesis during implantation. EMBO J. 2023 Sep 4;42(17):e113280 |
| 6 | J:219394 Boroviak T, Loos R, Bertone P, Smith A, Nichols J, The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. Nat Cell Biol. 2014 Jun;16(6):516-28 |
| 9 | J:82465 Bortvin A, Eggan K, Skaletsky H, Akutsu H, Berry DL, Yanagimachi R, Page DC, Jaenisch R, Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei. Development. 2003 Apr;130(8):1673-80 |
| 1 | J:112229 Bosman EA, Lawson KA, Debruyn J, Beek L, Francis A, Schoonjans L, Huylebroeck D, Zwijsen A, Smad5 determines murine amnion fate through the control of bone morphogenetic protein expression and signalling levels. Development. 2006 Sep;133(17):3399-409 |
| 3* | J:48570 Botquin V, Hess H, Fuhrmann G, Anastassiadis C, Gross MK, Vriend G, Scholer HR, New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2. Genes Dev. 1998 Jul 1;12(13):2073-90 |
| 1 | J:64333 Bowles J, Bullejos M, Koopman P, A subtractive gene expression screen suggests a role for vanin-1 in testis development in mice. Genesis. 2000 Jul;27(3):124-35 |
| 3* | J:164280 Bowles J, Feng CW, Spiller C, Davidson TL, Jackson A, Koopman P, FGF9 suppresses meiosis and promotes male germ cell fate in mice. Dev Cell. 2010 Sep 14;19(3):440-9 |
| 3* | J:87105 Bowles J, Teasdale RP, James K, Koopman P, Dppa3 is a marker of pluripotency and has a human homologue that is expressed in germ cell tumours. Cytogenet Genome Res. 2003;101(3-4):261-5 |
| 1 | J:149785 Bradford ST, Hiramatsu R, Maddugoda MP, Bernard P, Chaboissier MC, Sinclair A, Schedl A, Harley V, Kanai Y, Koopman P, Wilhelm D, The cerebellin 4 precursor gene is a direct target of SRY and SOX9 in mice. Biol Reprod. 2009 Jun;80(6):1178-88 |
| 1* | J:151715 Bradford ST, Wilhelm D, Bandiera R, Vidal V, Schedl A, Koopman P, A cell-autonomous role for WT1 in regulating Sry in vivo. Hum Mol Genet. 2009 Sep 15;18(18):3429-38 |
| 1 | J:70006 Brennan J, Lu CC, Norris DP, Rodriguez TA, Beddington RS, Robertson EJ, Nodal signalling in the epiblast patterns the early mouse embryo. Nature. 2001 Jun 21;411(6840):965-9 |
| 1* | J:334521 Burnet G, Feng CA, Cheung KMF, Bowles J, Spiller CM, Generation and characterization of a Ddx4-iCre transgenic line for deletion in the germline beginning at genital ridge colonization. Genesis. 2023 Mar;61(1-2):e23511 |
| 7 | J:203762 Burton A, Muller J, Tu S, Padilla-Longoria P, Guccione E, Torres-Padilla ME, Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo. Cell Rep. 2013 Nov 14;5(3):687-701 |
| 1 | J:185482 Burtscher I, Barkey W, Schwarzfischer M, Theis FJ, Lickert H, The Sox17-mCherry fusion mouse line allows visualization of endoderm and vascular endothelial development. Genesis. 2012 Jun;50(6):496-505 |
| 2* | J:139638 Cai KQ, Capo-Chichi CD, Rula ME, Yang DH, Xu XX, Dynamic GATA6 expression in primitive endoderm formation and maturation in early mouse embryogenesis. Dev Dyn. 2008 Sep 24;237(10):2820-2829 |
| 1 | J:196968 Campolo F, Gori M, Favaro R, Nicolis S, Pellegrini M, Botti F, Rossi P, Jannini EA, Dolci S, Essential role of Sox2 for the establishment and maintenance of the germ cell line. Stem Cells. 2013 Jul;31(7):1408-21 |
| 1* | J:165230 Carayannopoulos LN, Barks JL, Yokoyama WM, Riley JK, Murine trophoblast cells induce NK cell interferon-gamma production through KLRK1. Biol Reprod. 2010 Sep;83(3):404-14 |
| 5* | J:140626 Card DA, Hebbar PB, Li L, Trotter KW, Komatsu Y, Mishina Y, Archer TK, Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells. Mol Cell Biol. 2008 Oct;28(20):6426-38 |
| 17* | J:186276 Celebi C, van Montfoort A, Skory V, Kieffer E, Kuntz S, Mark M, Viville S, Tex 19 Paralogs Exhibit a Gonad and Placenta-Specific Expression in the Mouse. J Reprod Dev. 2012 Jul 3;58(3):360-5 |
| 3* | J:70069 Chang H, Matzuk MM, Smad5 is required for mouse primordial germ cell development. Mech Dev. 2001 Jun;104(1-2):61-7 |
| 5* | J:331510 Chang WF, Lin TY, Peng M, Chang CC, Xu J, Hsieh-Li HM, Liu JL, Sung LY, Survival Motor Neuron Enhances Pluripotent Gene Expression and Facilitates Cell Reprogramming. Stem Cells Dev. 2022 Nov;31(21-22):696-705 |
| 2 | J:179634 Chassot AA, Gregoire EP, Lavery R, Taketo MM, de Rooij DG, Adams IR, Chaboissier MC, RSPO1/beta-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary. PLoS One. 2011;6(10):e25641 |
| 2* | J:299356 Chassot AA, Le Rolle M, Jolivet G, Stevant I, Guigonis JM, Da Silva F, Nef S, Pailhoux E, Schedl A, Ghyselinck NB, Chaboissier MC, Retinoic acid synthesis by ALDH1A proteins is dispensable for meiosis initiation in the mouse fetal ovary. Sci Adv. 2020 May;6(21):eaaz1261 |
| 1 | J:133933 Chassot AA, Ranc F, Gregoire EP, Roepers-Gajadien HL, Taketo MM, Camerino G, de Rooij DG, Schedl A, Chaboissier MC, Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary. Hum Mol Genet. 2008 May 1;17(9):1264-77 |
| 5 | J:185786 Chawengsaksophak K, Svingen T, Ng ET, Epp T, Spiller CM, Clark C, Cooper H, Koopman P, Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice. Biol Reprod. 2012 Jan;86(1):1-12 |
| 3 | J:112232 Chazaud C, Rossant J, Disruption of early proximodistal patterning and AVE formation in Apc mutants. Development. 2006 Sep;133(17):3379-87 |
| 2 | J:108748 Chazaud C, Yamanaka Y, Pawson T, Rossant J, Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev Cell. 2006 May;10(5):615-24 |
| 3 | J:231798 Chen CY, Chan CH, Chen CM, Tsai YS, Tsai TY, Wu Lee YH, You LR, Targeted inactivation of murine Ddx3x: essential roles of Ddx3x in placentation and embryogenesis. Hum Mol Genet. 2016 July 15;25(14):2905-2922 |
| 2* | J:320425 Chen CY, Lee DS, Yan YT, Shen CN, Hwang SM, Lee ST, Hsieh PC, Bcl3 Bridges LIF-STAT3 to Oct4 Signaling in the Maintenance of Naive Pluripotency. Stem Cells. 2015 Dec;33(12):3468-80 |
| 2 | J:277240 Chen CY, Yu IS, Pai CH, Lin CY, Lin SR, Chen YT, Lin SW, Embryonic Cul4b is important for epiblast growth and location of primitive streak layer cells. PLoS One. 2019;14(7):e0219221 |
| 1 | J:316527 Chen HH, Welling M, Bloch DB, Munoz J, Mientjes E, Chen X, Tramp C, Wu J, Yabuuchi A, Chou YF, Buecker C, Krainer A, Willemsen R, Heck AJ, Geijsen N, DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells. Stem Cell Reports. 2014 Nov 11;3(5):892-904 |
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| 3 | J:301138 Chen SH, Lu CH, Tsai MJ, TCTP is Essential for Cell Proliferation and Survival during CNS Development. Cells. 2020 Jan 6;9(1):133 |
| 2 | J:225062 Chen SR, Zheng QS, Zhang Y, Gao F, Liu YX, Disruption of genital ridge development causes aberrant primordial germ cell proliferation but does not affect their directional migration. BMC Biol. 2013;11:22 |
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| 4* | J:124183 Cheng WC, Hsieh-Li HM, Yeh YJ, Li H, Mice lacking the Obox6 homeobox gene undergo normal early embryonic development and are fertile. Dev Dyn. 2007 Sep;236(9):2636-42 |
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| 3 | J:67053 Chuma S, Nakatsuji N, Autonomous transition into meiosis of mouse fetal germ cells in vitro and its inhibition by gp130-mediated signaling. Dev Biol. 2001 Jan 15;229(2):468-79 |
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| 1 | J:199463 Cockburn K, Biechele S, Garner J, Rossant J, The hippo pathway member nf2 is required for inner cell mass specification. Curr Biol. 2013 Jul 8;23(13):1195-201 |
| 8* | J:148410 Combes AN, Lesieur E, Harley VR, Sinclair AH, Little MH, Wilhelm D, Koopman P, Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development. Dev Dyn. 2009 May;238(5):1033-41 |
| 1 | J:158334 Combes AN, Spiller CM, Harley VR, Sinclair AH, Dunwoodie SL, Wilhelm D, Koopman P, Gonadal defects in Cited2-mutant mice indicate a role for SF1 in both testis and ovary differentiation. Int J Dev Biol. 2010;54(4):683-9 |
| 5 | J:167041 Cook MS, Munger SC, Nadeau JH, Capel B, Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background. Development. 2011 Jan;138(1):23-32 |
| 2 | J:112036 Costa Y, Speed RM, Gautier P, Semple CA, Maratou K, Turner JM, Cooke HJ, Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?. Hum Mol Genet. 2006 Aug 1;15(15):2324-34 |
| 1 | J:154783 Costello I, Biondi CA, Taylor JM, Bikoff EK, Robertson EJ, Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development. BMC Dev Biol. 2009;9:54 |
| 3 | J:105812 Covello KL, Kehler J, Yu H, Gordan JD, Arsham AM, Hu CJ, Labosky PA, Simon MC, Keith B, HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev. 2006 Mar 1;20(5):557-70 |
| 1* | J:163340 Cox BJ, Vollmer M, Tamplin O, Lu M, Biechele S, Gertsenstein M, van Campenhout C, Floss T, Kuhn R, Wurst W, Lickert H, Rossant J, Phenotypic annotation of the mouse X chromosome. Genome Res. 2010 Aug;20(8):1154-64 |
| 1* | J:222418 Czechanski A, Kim H, Byers C, Greenstein I, Stumpff J, Reinholdt LG, Kif18a is specifically required for mitotic progression during germ line development. Dev Biol. 2015 Jun 15;402(2):253-62 |
| 2 | J:239417 Dai HQ, Wang BA, Yang L, Chen JJ, Zhu GC, Sun ML, Ge H, Wang R, Chapman DL, Tang F, Sun X, Xu GL, TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling. Nature. 2016 Oct 27;538(7626):528-532 |
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